Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4358396 | Research in Microbiology | 2016 | 5 Pages |
Abstract
Nosocomial infections caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are a major concern worldwide. There is an urgent need to identify bacterial factors promoting survival and persistence of these organisms in the nosocomial environment. Here, we describe the presence of a gene cluster, containing the Clp ATPase ClpK, within a collection of Danish ESBL-producing E. coli isolates. The cluster conferred thermoprotection upon the isolates, and thus might facilitate survival on medical devices exposed to semi-high temperatures in a hospital setting.
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Authors
Erik J. Boll, Jakob Frimodt-Møller, Bente Olesen, Karen A. Krogfelt, Carsten Struve,