Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4358841 | Research in Microbiology | 2011 | 5 Pages |
Abstract
The vaginal microbiome, which harbors beneficial Lactobacillus strains, is believed to be a major host defense mechanism for preventing infections of the urogenital tract. It has been suggested that the gastrointestinal tract serves as a reservoir for lactobacilli that colonize the vagina. Using rhesus macaques, we examined whether oral delivery of human vaginal Lactobacillus jensenii 1153–1646, a GusA-producing strain, would result in colonization of the rectum and the vagina. Lactobacilli were identified from the vagina tracts of three macaques on the basis of β-glucuronidase enzyme production, 16S rRNA gene sequence and DNA homology using a repetitive sequence-based polymerase chain reaction.
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Authors
Laurel A. Lagenaur, Peter P. Lee, Dean H. Hamer, Brigitte E. Sanders-Beer,