Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4359043 | Research in Microbiology | 2009 | 8 Pages |
Abstract
General and regulated proteolysis in bacteria is crucial for cellular homeostasis and relies on high substrate specificity of the executing AAA+ proteases. Here we summarize the various strategies that tightly control substrate degradation from both sides: the generation of accessible degrons and their specific recognition by AAA+ proteases and cognate adaptor proteins.
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Authors
Ronny Schmidt, Bernd Bukau, Axel Mogk,