Article ID Journal Published Year Pages File Type
4359125 Research in Microbiology 2009 6 Pages PDF
Abstract

Structural analysis supported by biochemical, mutagenesis and computational evidence, revealed that the contemporary ribosome's active site is a universal symmetrical pocket made of ribosomal RNA. This pocket seems to be the remnant of the proto-ribosome, a dimeric RNA assembly evolved by gene duplication, capable of autonomously catalyzing peptide bond formation and non-coded amino acid polymerization.

Keywords
Related Topics
Life Sciences Immunology and Microbiology Applied Microbiology and Biotechnology
Preview
The evolving ribosome: from non-coded peptide bond formation to sophisticated translation machinery
Authors
, , , ,