| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4359473 | Research in Microbiology | 2007 | 7 Pages |
Abstract
In enterobacteria, acid stress induces expression of the cad system which is involved in maintaining intracellular pH at levels compatible with cell survival. Despite its crucial role, the cad operon is silenced in Shigella and in other pathogenic Escherichia coli. In the present review, we will address the question of why and how the cad locus has been sacrificed for the sake of optimal expression of virulence traits.
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Authors
Gianni Prosseda, Maria Carmela Latella, Marialuisa Barbagallo, Mauro Nicoletti, Rasha Al Kassas, Mariassunta Casalino, Bianca Colonna,