| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4371026 | Experimental Parasitology | 2015 | 12 Pages |
Abstract
Highlights
- Croton caudatus leaf extracts have been evaluated against Leishmania âdonovani infection.
- Semi-purified Hexane extract was found to be most effective growth inhibitor.
- It could alter the biochemical parameters in promastigotes and inhibit amastigotes.
- It could induce the release of NO, IL-12 and TNF-α in infected macrophages.
- Oral therapy of the active extract could induce the release of IFN-γ in vivo.
- Croton caudatus leaf extracts have been evaluated against Leishmania âdonovani infection.
- Semi-purified Hexane extract was found to be most effective growth inhibitor.
- It could alter the biochemical parameters in promastigotes and inhibit amastigotes.
- It could induce the release of NO, IL-12 and TNF-α in infected macrophages.
- Oral therapy of the active extract could induce the release of IFN-γ in vivo.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Somaditya Dey, Debarati Mukherjee, Sondipon Chakraborty, Suvadip Mallick, Aritri Dutta, Joydip Ghosh, Ningombam Swapana, Swatilekha Maiti, Narayan Ghorai, Chingakham Brajakishor Singh, Chiranjib Pal,