Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4371047 | Experimental Parasitology | 2014 | 10 Pages |
Abstract
- Mechanisms of PQ and LM resistance in Plasmodium berghei ANKA.
- No polymorphisms in Pbcrt and Pbmdr1 genes.
- High expression of ggcs, gst, and vcx1 genes associated with PQ and LM resistance.
- Increased vp2 transcript associated with PQ resistance only.
- High GSH levels and elevated GST enzyme activity in PQ and LM resistance.
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Authors
Daniel Kiboi, Beatrice Irungu, Jennifer Orwa, Luna Kamau, Lynette Isabella Ochola-Oyier, Joseph Ngángá, Alexis Nzila,