Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4371136 | Experimental Parasitology | 2013 | 11 Pages |
Abstract
- Annexin-V positive and TUNEL positive cells observed upon spinigerin exposure.
- ROS machinery was involved in spinigerin mediated apoptosis like death.
- Mitochondrial membrane potential was collapsed without caspase like activity.
- The infection rate was reduced by 20% upon exposure to 150 μM spinigerin.
- Computational analysis suggests spiningerin interacts with trypanothione reductase.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
A.H. Sardar, S. Das, S. Agnihorti, M. Kumar, A.K. Ghosh, K. Abhishek, A. Kumar, B. Purkait, M.Y. Ansari, P. Das,