Article ID Journal Published Year Pages File Type
4371185 Experimental Parasitology 2013 6 Pages PDF
Abstract
► Low concentration of T. cruzi induces PLC-γ and ERK1/2 MAPK pathways activation during ex vivo infection of human placenta. ► High concentration of T. cruzi induces a moderate PLC-γ pathway activation during ex vivo infection of human placenta. ► High concentration of T. cruzi inhibits ERK1/2 MAPK pathway during ex vivo infection of human placenta. ► Inhibition of any of those signal transduction pathways do not prevent the ex vivo infection of human placenta by T. cruzi.
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Life Sciences Immunology and Microbiology Parasitology
Preview
Phospholipase C gamma and ERK1/2 Mitogen Activated Kinase Pathways are differentially modulated by Trypanosoma cruzi during tissue invasion in human placenta
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