Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4371287 | Experimental Parasitology | 2011 | 10 Pages |
Abstract
⺠In vitro schistosomula and adult Schistosoma mansoni were more affected by the erythro mefloquine derivatives when compared to the threo drugs. ⺠In vivo, all mefloquine isomers and racemates achieved statistically significant total and female worm burden reductions ranging between 65.4% and 100%. ⺠Microcalorimetry is a useful tool to study drug effects on schistosomes.
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Authors
Theresia Manneck, Olivier Braissant, William Ellis, Jennifer Keiser,