Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4409328 | Chemosphere | 2013 | 6 Pages |
Magnetic ionic liquids (MILs) are new solvents with an interesting broad of applications however their toxicity is still an open issue. In this paper we report the toxicity of [C8MIM] and [Choline-Cn] based magnetic ionic liquids assessed in two human cell lines: normal skin fibroblasts (CRL-1502) and colorectal adenocarcinoma cells (CaCo-2), acquiring this last characteristics of human enterocytes after differentiation. The results showed that [CoCl4] and [MnCl4] are more prone to generate cytotoxicity.
• Imidazolium and choline based cations were combined with magnetic anions to produce magnetic ionic liquids. • The used magnetic anions were [FeCl4], [GdCl6], [CoCl4] and [MnCl4]. • Human cell lines were exposed to these magnetic ionic liquids for prediction of their toxic potential. • Results indicate that [CoCl4] and [MnCl4] are likely the most toxic.