| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4409372 | Chemosphere | 2013 | 8 Pages |
New assays with HepG2 cells indicate that Indigo Carmine (IC), a dye that is widely used as additive in many food and pharmaceutical industries exhibited cytotoxic effects. This work describes the development of a bicomponent nanostructured Ti/TiO2/WO3 electrode prepared by “template” method and investigates its efficiency in a photoelectrocatalytic method by using visible light irradiation and applied potential of 1 V. After 2 h of treatment there are reduction of 97% discoloration, 62% of mineralization and formation of three byproducts assigned as: 2-amine-5-sulfo-benzoic acid, 2,3-dioxo-14-indole-5-sulfonic acid, and 2-amino-α-oxo-5-sulfo-benzeneacetic acid were identified by HPLC-MS/MS. But, cytotoxicity was completely removed after 120 min of treatment.
► IC exhibits genotoxic effects on HepG2 cells and is no harmful after treatment. ► Nanostrucutured Ti/TiO2/WO3 electrode are easily prepared by template. ► Cytotoxicity is negligible after treatment with visible light and potential of 1 V.
