Oral administration of potassium bromate, a major water disinfection by-product, induces oxidative stress and impairs the antioxidant power of rat blood

Article ID	Journal	Published Year	Pages	File Type
4409846	Chemosphere	2012	7 Pages	PDF

Abstract

âº Oral administration of potassium bromate reduces anti-oxidant power of rat blood. âº The activities of anti-oxidant enzymes are altered in rat erythrocytes and plasma. âº The effect of potassium bromate is reversible; it is maximum at 2Â d after administration and then recovery takes place.

Keywords

GPX ALT DTNB LPO FRAP GST GSH G6PD CAT KBrO3 DPPH MDA 2,2-diphenyl-1-picrylhydrazyl Hydrogen peroxide AST Aspartate aminotransferase Alanine aminotransferase ferric reducing ability of plasma BUN Anti-oxidant malonaldehyde metHb methemoglobin blood urea nitrogen Hemoglobin H2O2 Potassium bromate Lipid peroxidation Catalase reduced glutathione glutathione-S-transferase glutathione reductase Glutathione peroxidise glucose 6-phosphate dehydrogenase