Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4411800 | Chemosphere | 2010 | 7 Pages |
Abstract
Effect of potassium salt of perfluorooctane sulfonic acid (PFOS) on the osmoregulation of marine teleost (blackrock fish), Sebastes schlegeli, was investigated under varying salinities, by monitoring serum osmolality, Na+, K+, Clâ, Ca2+ and Mg2+ concentrations in serum, serum glucose, and gill Na+-K+ ATPase (NKA) activity. The fish was acclimatized to four salinity levels (10, 17.5, 25, and 34 psu) for 2 weeks before a 6-d exposure to 100 or 1000 μg Lâ1 of PFOS. Six fish from each exposure group were sampled at 24, 48, and 144 h after exposures, and serum, liver and gills were collected for analysis. NKA activity decreased by 34% and 31% relative to control at salinity levels of 25 and 34 psu, respectively, following exposure to 1000 μg Lâ1 PFOS. PFOS did not affect serum osmolality, Na+, Clâ, Ca2+ and Mg2+ concentrations; however, serum K+ concentration increased during initial exposure period and then decreased after 144 h. Serum glucose levels decreased with increasing PFOS concentrations, implying high energy demand in response to exposure. Overall, PFOS exposure impaired NKA activity, altered potassium ion concentrations in serum, and reduced serum glucose levels while no other effects on serum concentrations of ionic salts were observed.
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Authors
Junho Jeon, Han Kyu Lim, Kurunthachalam Kannan, Sang Don Kim,