| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4421056 | Ecotoxicology and Environmental Safety | 2012 | 7 Pages |
The objective of this study is to determine the effect of sublethal copper on the glutathione system and carotenoids of Penaeus indicus postlarvae (PL) when subjected to short- and long-term exposure in the laboratory. The PL were exposed to 0.1641 ppm (sublethal) copper for a period of 30 days with sampling intervals of 24, 48, 96 h and 10, 20, 30 days. Variations in the activity of Glutathione reductase (GR), Glutathione peroxidase (GPx) and Glutathione-S-transferase (GSTase) were measured as biomarkers of toxicity. A significant (P<0.05) increase in the GR and GPx activity of the exposed PL till 20 days of exposure and thereafter a significant decrease indicates susceptibility of the PL to oxidative stress upon chronic exposure. Similarly, a significant decrease in GSTase activity during long-term exposures in the exposed PL reflects possible failure of the detoxification system. A possible role of carotenoids to combat oxidative stress against copper toxicity is also discussed.
► Effect of sublethal Cu on glutathione system, carotenoids of P. indicus postlarvae. ► GSTase, GPx and GR activity decreases in exposed postlarvae upon chronic exposure. ► This indicates susceptibility of PL to oxidative stress upon chronic exposure. ► Decrease in GSTase activity reflects possible failure of the detoxification system. ► Carotenoids can be used as biomarker; P. indicus PL as bioindicator of Cu pollution.
