| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4421837 | Ecotoxicology and Environmental Safety | 2010 | 6 Pages |
The toxicity of the nonylphenol polyethoxylate, R-11 and the neonicotinoid insecticide, imidacloprid were evaluated on the crustacean, Ceriodaphnia dubia Richard. These compounds were evaluated separately and as a mixture because they are applied for pest control and may exist as a binary mixture in surface water. Acute mortality estimates (48 h) were developed followed by population-level studies after chronic exposure. LC50s and 95% CL for R-11 and imidacloprid were 9241 (8521–9842) μg/l and 2.1 (1.1–3.4) μg/l, respectively. In the population study, C. dubia were exposed to concentrations equivalent to the acute LC25 for R-11 (8090 μg/l) and imidacloprid (0.3 μg/l) separately and as a mixture for 8 d. The results of the chronic study indicated that R-11 had a greater impact on population parameters than imidacloprid and the mixture had a greater impact than either compound alone. For example, the total number of individuals at the end of the chronic study was 73%, 19%, and 6% of the control for imidacloprid, R-11, and the binary mixture, respectively. Additionally, exposure to R-11, imidacloprid, and the mixture resulted in 52%, 10%, and 91% reductions in population growth rate compared to the control, respectively. The results of this study indicate that when combined, R-11 and imidacloprid act in a more than additive manner. Therefore, it is important that their potential effects on aquatic organisms be evaluated together.
