| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 44273 | Applied Catalysis A: General | 2006 | 4 Pages |
Abstract
Natural and synthetic phosphates were used as heterogeneous catalysts to promote the Friedel–Crafts reaction between 5-bromohydantoin and aromatic compounds. In the case of phenol, ortho and para isomers were always obtained. Fluoroapatite (FAP) and natural phosphate (NP) lead to the best selectivity. However, the best overall yield of 5-(hydroxyphenyl)hydantoin was obtained when hydroxyapatite (HAP) was used. This method can also be applied to other aromatics, such as anisole and thiophene. In some cases, activation by zinc bromide (ZnBr2) was also investigated in order to increase the activity of these phosphate catalysts.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Rachid Tahir, Klaus Banert, Saïd Sebti,