Exposure assessment of phthalates in non-occupational populations in China

Phthalates have been used worldwide and are ubiquitous in environmental media and human bodies. Based on existing data on phthalate concentrations, distributions of phthalates in the environment and their exposure assessment to non-occupational populations in China can be evaluated. Fifty-three studies, published from January 2000 to October 2010, were reviewed and their data were analyzed in this study. Geographic information system (GIS) was used in mapping the published data of phthalate concentrations and their distributions in environmental media, while scatter diagrams were applied to show the time trends for phthalate concentrations in various environmental media. Results showed that there was a time-dependent increase in ∑ phthalates (total phthalates) and DEHP concentrations in air during the past 10 years; phthalate concentrations varied in different areas, among which Guangdong and northeast China were the most polluted. Using Clark's equations, daily intake of ∑ phthalates and DEHP in the Pearl River Delta and the Yangtze River Delta was estimated from consumption of contaminated food, water and air. Results showed that daily intake of ∑ phthalates and DEHP was 128.63 and 61.29 μg/kg BW/d for adults in the Pearl River Delta, which is significantly higher than those residing in the Yangtze River Delta (33.87 and 24.68 μg/kg BW/d).

► Phthalate distributions and concentrations in environment were shown by GIS. ► There was a time-dependent increase in phthalate levels in air during past ten years. ► Daily intake of Σphthalates was 128.63 mg/kg BW/d for adults in the Pearl River Delta. ► Daily intake of Σphthalates was 33.87 mg/kg BW/d for adults in the Yangtze River Delta. ► Results provide valuable data for further risk assessment of phthalates in China.