Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
442962 | Journal of Molecular Graphics and Modelling | 2009 | 5 Pages |
Abstract
We put forward a novel compact 2-D graphical representation of proteins based on the concept of virtual genetic code and a four-color map. The novel graphical representation uniquely represents proteins and allows one to easily and quickly visually observe and inspect similarity/dissimilarity between them. It also leads to a novel protein descriptor, a 10-dimensional vector derived from a novel structure matrix S associated with the map. The introduced numerical characterization of proteins is not only useful for their comparative study, but also for cataloguing information on a single protein. The approach is illustrated with the A chain of human insulin and the A chain of human insulin analogue glargine.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Milan Randić, Ketij Mehulić, Damir Vukičević, Tomaž Pisanski, Dražen Vikić-Topić, Dejan Plavšić,