Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4430850 | Science of The Total Environment | 2011 | 7 Pages |
Abstract
⺠A subset of US boys aged 3-5 years, with both plasma methylmalonic acid (MMA) above and serum folate levels below the sample medians, showed a significant inverse association between total blood mercury and plasma homocysteine. This relationship was not evident in all other US boys and girls aged 3-5 years. ⺠Boys with higher MMA and lower serum folate levels had significantly higher mean plasma homocysteine levels compared to all other boys. ⺠Boys with higher MMA and lower serum folate levels had significantly lower mean total blood mercury levels compared to girls. ⺠Among boys with both higher MMA and lower serum folate levels, total blood mercury was significantly inversely associated with homocysteine at levels of mercury exposure well below the 5.8 μg/L reference dose for maternal cord blood methylmercury exposure associated with adverse neurobehavioral endpoints.
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Authors
Carolyn M. Gallagher, Jaymie R. Meliker,