Application of DPD in the design of polymeric nano-micelles as drug carriers

•This is a review on the studies employing DPD for the simulation of drug loading and release.•The DPD is successful in comparing the ability of a carrier for loading and release of the drugs.•To design of new carriers, the DPD results on similar systems should be validated by available data.

Developing new drug carrier systems are of a great importance in the treatment approach for a wide range of diseases. The simulation techniques can be valuable for decreasing the time and cost of developing novel drug carriers. Among the simulation methods there are a vast number of studies using dissipative particle dynamics (DPD) method for the prediction of different aspects of polymeric nano-micelles for encapsulating drugs. Here, we reviewed the results of the studies employing DPD for the simulation of drug loading and release in different polymeric micelles carriers. In some cases the simulation results were compared with the experimental results by the authors that were demonstrated the reliability of the DPD predictions.

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