Article ID Journal Published Year Pages File Type
4434143 Science of The Total Environment 2006 11 Pages PDF
Abstract

An approach involving chemical and biological techniques was taken for the detection and quantification of the marine toxin okadaic acid (OA) in mussels from Thermaikos Gulf, Greece, during a 4-month DSP episode that occurred in 2002. Samples were analyzed using the mouse bioassay, high performance liquid chromatography (HPLC) with fluorimetric detection and an enzyme-linked immunosorbent assay (ELISA). Okadaic acid was quantifiable at three different sites of Thermaikos Gulf reaching a maximum concentration of 36 μg/g hepatopancreas. High correlation was revealed between results derived from HPLC and ELISA (R2 = 0.998), while 91% consistency between HPLC and the mouse bioassay results was observed.

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