Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4551325 | Marine Environmental Research | 2010 | 4 Pages |
Abstract
The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We developed a “multi-trial diagnostic tool” (based on field and in vitro studies), combining molecular biomarkers (western blot of CYP1A1, CYP2B) and gene expression (qRT-PCR of HSP70, ERα, AHR, E2F-1) with the analysis of OCs, PAHs and PBDEs. The study revealed a higher level of toxicological stress in the Mediterranean fin whales.
Keywords
Related Topics
Physical Sciences and Engineering
Earth and Planetary Sciences
Oceanography
Authors
Maria Cristina Fossi, Jorge Urban, Silvia Casini, Silvia Maltese, Giacomo Spinsanti, Cristina Panti, Serena Porcelloni, Simone Panigada, Giancarlo Lauriano, Carlos Niño-Torres, Lorenzo Rojas-Bracho, Begoña Jimenez, Juan Muñoz-Arnanz, Letizia Marsili,