Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4625213 | Advances in Applied Mathematics | 2008 | 28 Pages |
Abstract
The Kimura 3-parameter model on a tree of n leaves is one of the most used in phylogenetics. The affine algebraic variety W associated to it is a toric variety. We study its geometry and we prove that it is isomorphic to a geometric quotient of the affine space by a finite group, which is completely described. As a consequence, we are able to study the singularities of W and prove that the biologically meaningful points are smooth points. Then we give an algorithm for constructing a set of minimal generators of the localized ideal at these points, for an arbitrary number of leaves n. This leads to a major improvement of phylogenetic reconstruction methods based on algebraic geometry.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics