Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4629349 | Applied Mathematics and Computation | 2012 | 11 Pages |
Abstract
This paper is concerned with the estimation of the parameters of interest in the drift coefficient of a stochastic Gompertz model with logarithmic therapeutic functions. The maximum likelihood method produces non-linear equations and the estimation of these parameters, specially of the tumor growth deceleration factor, have only been achieved to date through numerically-based approaches. The proposed method in this paper provides explicit expressions for the parameter estimators which, we shall be able, in future work, to study its statistical properties.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
El Kettani Moummou, R. Gutiérrez, R. Gutiérrez-Sanchez,