| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4632408 | Applied Mathematics and Computation | 2010 | 6 Pages |
Abstract
A viral infection model with immune circadian rhythms is investigated in this paper. By employing the persistence theory, we establish a threshold between the extinction and the uniform persistence of the disease. These results can be used to explain the oscillation behaviors of virus population, which were observed in chronic HBV or HCV carriers. Further, numerical simulations indicate that the dynamics of the lytic component of cytotoxicity T cells (CTLs) is crucial to the outcome of a viral infection.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Aijun Fan, Kaifa Wang,