Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4634262 | Applied Mathematics and Computation | 2008 | 8 Pages |
Abstract
The aim of this work is the numerical simulation of the formation of hydrogen-bonded base pairs between adenine, thymine, guanine and cytosine. We use a Monte Carlo diffusion simulation with geometric (molecular distances and orientation) and energetic (acceptance proportional to the Boltzmann factor) criteria. Our results show that the occurrence of the different types of base pairs is strongly influenced by base geometry. Such results can help to understand some mechanisms, which occur at processes related to mutation.
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Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Sani de C.R. Da Silva, Dimitrios Samios, P.A. Netz, Dagoberto A.R. Justo, A.L. De Bortoli,