Article ID Journal Published Year Pages File Type
4639523 Journal of Computational and Applied Mathematics 2013 9 Pages PDF
Abstract

We consider a free boundary problem modeling tumor growth where the model equations include a diffusion equation for the nutrient concentration and the Stokes equation for the proliferation of tumor cells. For any positive radius RR, it is known that there exists a unique radially symmetric stationary solution. The proliferation rate μμ and the cell-to-cell adhesiveness γγ are two parameters for characterizing “aggressiveness” of the tumor. We compute symmetry-breaking bifurcation branches of solutions by studying a polynomial discretization of the system. By tracking the discretized system, we numerically verified a sequence of μ/γμ/γ symmetry breaking bifurcation branches. Furthermore, we study the stability of both radially symmetric and radially asymmetric stationary solutions.

Related Topics
Physical Sciences and Engineering Mathematics Applied Mathematics
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