| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4756781 | Catalysis Today | 2017 | 7 Pages |
Abstract
We report the p-nitrobenzyl ester of a meso-carboxyl BODIPY as a new fluorogenic probe for the monitoring of nitroreductase acitivity. It showed remarkable fluorescence enhancement (â¼220-fold), high sensitivity (detection limit of 0.9Â ng/mL), and high selectivity for nitroreductase over other biorelated species. In vitro cell studies confirmed its utility for the rapid fluorescence imaging of hypoxic cancer cells.
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Physical Sciences and Engineering
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Catalysis
Authors
Zi Wang, Gaurav Laddha, Swarom Kanitkar, James J. Spivey,