| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4761099 | Pathology | 2012 | 5 Pages |
Abstract
We have described here a molecular tool to study mutations that affect a-globin pre-mRNA splicing and translation. We confirm in silico predictions of the consequences of the HBA1:c.301-3C>G mutation, proving aberrant RNA splicing and the production of a truncated α-globin protein.
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Authors
Talal Qadah, Jill Finlayson, Christopher Newbound, Nicole Pell, Michelle Jennens, Paula Holmes, Dianne Grey, John Beilby, Reza Ghassemifar,