A sensitive sodium dodecyl sulfonate functionalized graphene hybrid SnO2 nanoparticles composite modified glassy carbon electrode for detecting daphnetin

•SDS-GN/SnO2 nanocomposite was built via facile one-pot synthesis.•A new electrochemical sensor for determining daphnetin was fabricated by SDS-GN/SnO2 composite.•The sensor displayed higher sensitivity and wider linear range.•The synergistic effect of SDS-GN and SnO2 improved the sensor's performance.

A sensitive electrochemical sensor based on sodium dodecyl sulfonate (SDS) functionalized graphene hybrid SnO2 nanoparticles (SDS-GN/SnO2) composite was fabricated via one-pot synthesis. The SDS-GN/SnO2 nanocomposite significantly increased the redox activity of daphnetin due to the individual merit and mutual effect of SDS-GN and SnO2 nanoparticles which improved the performance of the electrochemical sensor with high sensitivity. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) measurements were used for the detection of daphnetin. Under the optimal conditions, the oxidation peak currents of daphnetin increased proportionally to the concentration within the range of 0.03-1.0 μmol L− 1 and 1.0-8.0 μmol L− 1, and the limit of detection was 8.0 nmol L− 1. The proposed modified electrode was highly sensitive and was successfully applied to determine daphnetin in the pharmaceutical sample with satisfactory recoveries. The as-prepared SDS-GN/SnO2/GCE electrochemical sensor offers a feasible way for designing simpler, low cost sensors based on SnO2 nanoparticles.

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