Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4909287 | Journal of Saudi Chemical Society | 2017 | 6 Pages |
Abstract
The N-heterocyclic carbene silver(I) complex 1,3-bis(4-methylbenzyl)imidazol-2-ylidene silver chloride was applied as the effective catalyst for the three-component carboxylative coupling of terminal alkynes, butyl iodide and carbon dioxide. The reaction proved to be highly efficient when using 2Â mol% of 1,3-bis(4-methylbenzyl)imidazol-2-ylidene silver(I) chloride as the catalyst in the presence of 1.5 equiv. of Cs2CO3 as the base in DMF. This reaction shows good selectivity and substituent-loading capability, in which various functionalized 2-alkynoates were obtained in good yields under very mild conditions.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Zhi-Zhi Zhang, Rui-Jie Mi, Fang-Jie Guo, Jing Sun, Ming-Dong Zhou, Xiang-Chen Fang,