Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4909502 | Journal of Saudi Chemical Society | 2016 | 6 Pages |
Abstract
Fused ring 3,4-dihydropyrimidin-2(1H)-ones and thiones were synthesized by the one-pot three component condensation of 6-methoxy-1-tetralone, aromatic aldehydes and urea or thiourea under solvent-free conditions at 120 °C utilizing poly(4-vinylpyridinium)hydrogen sulfate as Bronsted acid catalyst. This methodology has an advantage of good yields, shorter reaction times, straight forward workup and reusability of the catalyst over five additional times without losing its activity and product yield.
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Authors
B. Janardhan, B. Rajitha, Peter A. Crooks,