Article ID Journal Published Year Pages File Type
4909503 Journal of Saudi Chemical Society 2016 4 Pages PDF
Abstract

In this paper, we describe a two-step synthesis of a series of substituted tetrahydroquinoline analogies. In the first step α,α′-bis(substituted-benzylidene)cycloalkanones are reacted with malononitrile to afford 2-amino-3-cyano-4H-pyrans. The second step involves the conversion of pyrans into 2-amino-5,6,7,8-tetrahydroquinoline-3-carbonitrile derivatives using NH4OAC.

Related Topics
Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
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