Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
49289 | Catalysis Communications | 2015 | 4 Pages |
Abstract
We report, herein, on palladium-catalyzed direct arylation of difluorobenzenes and dichlorobenzenes bearing benzoxazole or benzothiazole moieties, which don't act as directing groups. With moderate electron-withdrawing substituents on the aryl bromides as coupling partners, the reaction proceeds nicely using phosphine-free PdCl2 catalyst, and potassium pivalate/dimethylacetamide (PivOK/DMA) as catalytic system. The reaction was regioselective and occurred at the less hindered ortho-positions of fluorine or chlorine atoms.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Fatma Abdellaoui, Hamed Ben Ammar, Jean-François Soulé, Henri Doucet,