| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4930764 | European Neuropsychopharmacology | 2017 | 13 Pages |
Abstract
This QSP platform, combined with similar readouts for motor symptoms, negative symptoms and cognitive impairment has the potential to improve our understanding of drug effects in schizophrenia patients.
Keywords
MSNQSPglobus pallidus externaPANSSGPiSTNGPCRN-methyl-d-aspartateGPENMDAG-protein coupled receptorSchizophreniaglobus pallidus internasubstantia nigraPositron emission tomographyCombination therapyDrug treatmentCNSDopamineSeroquelCentral Nervous systemsQuantitative systems pharmacologySystems pharmacologyphosphodiesterase 10Apositive and negative syndrome scaleSubthalamic nucleusPET
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Authors
Athan Spiros, Patrick Roberts, Hugo Geerts,