Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4930835 | European Neuropsychopharmacology | 2016 | 5 Pages |
Abstract
This reanalysis of data demonstrates that anti-histaminergic activity is the strongest predictor of weight gain with antidepressants. These results further stress a reclassification of antidepressants according to their pharmacodynamic properties, and suggest avoiding prescribing antidepressants with an anti-histaminergic profile to patients at risk for cardio-metabolic disturbances.
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Authors
Virginio Salvi, Claudio Mencacci, Francesco Barone-Adesi,