Article ID Journal Published Year Pages File Type
49334 Catalysis Communications 2016 5 Pages PDF
Abstract

•Chitosan nanoparticles as an excellent biopolymer catalytic system in organic reaction•Introducing nanochitosan for the synthesis of 2-aminothiazoles•Generality of the catalyst, easiness of separation, and recycled several times

A convenient and efficient method is described for the synthesis of 2-aminothiazoles by one-pot reaction of ketone and thiourea using chitosan nanoparticles under mild condition. Nanochitosan was used as a biodegradable and green catalyst for this reaction in satisfactory yields. The attractive advantages of the present process include easy isolation of products, milder and cleaner conditions, higher purity and yields and easier work-up procedure.

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Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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