Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4933574 | Psychiatry Research | 2017 | 14 Pages |
Abstract
SH and ToSH amounts were found to be insufficient in untreated schizophrenia patients. Additionally, according to the results of the study, thiol/disulfide homeostasis was also disturbed by a shift to the disulfide bond formation side. This might affect the neurotransmission processes, which are known to be related with many symptoms observed in schizophrenia. The replacement of the thiol gap and the reduction of excess SS amounts might have a positive effect in supporting therapy for schizophrenia patients.
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Authors
Canan Topcuoglu, Abdurrahim Bakirhan, Fatma Meric Yilmaz, Salim Neselioglu, Ozcan Erel, Safak Yalcin Sahiner,