Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4933732 | Psychiatry Research | 2017 | 32 Pages |
Abstract
Depressed adults with significant childhood ADHD symptoms had a specific pattern of their major depressive episode compared to depressed patients without such symptoms. Subjects with childhood ADHD symptoms were more likely to report lifetime symptoms of mania/hypomania and to have a parent with type I or II bipolar disorder. The developmental trajectories of familial risk for lifetime bipolar symptoms showed that parental bipolar disorder influenced lifetime bipolar symptoms both through a direct pathway and an indirect pathway involving childhood ADHD symptoms. Childhood ADHD and number of depressive symptoms both made direct contributions to lifetime bipolar symptoms.
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Authors
D. Purper-Ouakil, MC Porfirio, Y. Le Strat, B. Falissard, P. Gorwood, G. Masi,