Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4934375 | Psychoneuroendocrinology | 2017 | 23 Pages |
Abstract
Gcgrâ/â mice are protected against olanzapine-induced increases in blood glucose. This is likely a result of reductions in liver glucose output, perhaps secondary to decreases in PEPCK and G6Pase protein content. Our findings highlight the central role of the liver in mediating olanzapine-induced disturbances in glucose homeostasis.
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Authors
Laura N. Castellani, Willem T. Peppler, Charles D. Sutton, Jamie Whitfield, Maureen J. Charron, David C. Wright,