| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4935347 | Seizure | 2017 | 22 Pages |
Abstract
CSE becomes super-refractory after more than 24Â h of appropriate treatments and may last weeks. Several anaesthetics have been proposed but evidence is scarce. Autoimmune refractory CSE has been recently identified, and early treatment with immuno-modulatory agents (corticosteroids and IV immunoglobulins and also second-line agents such as cyclophosphamide and rituximab followed by chronic immunosuppressive treatment) is now recommended by many experts.
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Authors
Gaetano Zaccara, Gianfranco Giannasi, Roberto Oggioni, Eleonora Rosati, Luciana Tramacere, Pasquale Palumbo, on behalf of the convulsive status epilepticus study group of the uslcentro Toscana,