| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4935408 | Seizure | 2017 | 8 Pages |
Abstract
The main effects of VPA on bone metabolism involve a decrease in osteoblast proliferation, changes in collagen synthesis as well as an induction of vitamin D catabolism. Apart from these direct actions of VPA in bone, indirect effects affecting other endocrine organs also contribute to VPA-induced bone loss.
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Authors
Dimitris A. Pitetzis, Martha G. Spilioti, John G. Yovos, Maria P. Yavropoulou,