Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS

Article ID	Journal	Published Year	Pages	File Type
4953133	Journal of Molecular Graphics and Modelling	2017	62 Pages	PDF

Keywords

Lactobacillus casei dhfr Escherichia coli Trichinella spiralis dihydrofolate reductase Crystal structures thymidylate synthase Molecular docking Caenorhabditis elegans

Related Topics

Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry

Preview

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS

Authors

Adam JarmuÅa, Piotr Wilk, Piotr Maj, Jan Ludwiczak, Anna DowierciaÅ, Katarzyna Banaszak, Wojciech Rypniewski, Joanna CieÅla, Magdalena DÄbrowska, Tomasz FrÄczyk, Agnieszka K. Bronowska, Jakub Jakowiecki, SÅawomir Filipek, Wojciech Rode,