| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4953294 | Journal of Molecular Graphics and Modelling | 2016 | 20 Pages |
Abstract
The transmembrane process of rofecoxib at different concentrations was simulated using molecular simulation method. Increasing concentration makes it favorable for rofecoxib to partition into bilayer. Our results show that permeability of one drug is not only dependent on drug concentration, but also related to drug hydrophobicity.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Huanjie Wang, Fancui Meng,