Synthesis and characterization of sulfonated-phenylacetic acid coated Fe3O4 nanoparticles as a novel acid magnetic catalyst for Biginelli reaction

•Interaction between sulfonated-phenylacetic acid coated Fe3O4 nanoparticles lead to good chemical stability.•This new catalyst exhibited high catalytic activity for Biginelli reaction.•3,4–dihydropyrimidin–2(1H)–ones were synthesized under mild reaction conditions.

In this paper, we wish to report the synthesis and characterization of sulfonated-phenylacetic acid coated on Fe3O4 nanoparticles by a simple method. This catalyst was effectively employed as a novel acid magnetic catalyst for the one-pot synthesis of different 3,4-dihydropyrimidin-2(1H)-ones under mild and solvent-free conditions. This catalyst was easily prepared and showed excellent level of reusability.

Graphical abstractSulfonated-phenylacetic acid coated on Fe3O4 nanocomposite was successfully prepared by a simple method, which was effectively employed as a novel acid magnetic catalyst for the synthesis of various 3,4-dihydropyrimidin-2(1H)-ones under mild conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide