| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 49848 | Catalysis Communications | 2012 | 4 Pages |
In this paper, we report a new solvent-free catalytic method using the magnetic nano Fe3O4 and CuFe2O4 as competent heterogeneous catalysts for the stereo- and regioselective reactions of epoxides with indoles/pyrroles, which gave the C-alkylated indoles/pyrroles. Chiral epoxides gave the alkylated indoles with a complete inversion of stereochemistry.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Magnetic Fe3O4 and CuFe2O4 nanoparticles as competent heterogeneous catalysts. ► Highly stereo-, regioselective reaction of epoxides with indoles and pyrroles. ► Chiral epoxides gave the C-alkylated indoles with complete inversion. ► Solvent-free reaction conditions, simple work-up and green protocol. ► Fe3O4 and CuFe2O4 nanoparticles are recoverable and recyclable catalysts.
