| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4985584 | Surfaces and Interfaces | 2017 | 6 Pages |
Abstract
As reported, the optimal size of hemoglobin-based oxygen carriers (HBOCs) should be preferably less than 1 µm and more than 100 nm. In this study, we employed manganese carbonate (MnCO3) for the production of preferably size multilayer hemoglobin (Hb) based sphere with glutaraldehyde (GA) as the crosslinking agent. By comparison, it can be found that {Hb/GA}5 also has a higher sensitivity to oxygen, stronger carrying-oxygen ability and more stable properties than that of {Hb/GA}1. However, MnCO3 based Hb-loaded spheres did not show better performance than CaCO3 based Hb-loaded spheres. 177
Keywords
PBSGCESCEDPVglassy carbon electrodeSaturated Calomel ElectrodeDirect electrochemistryEISHemoglobin-based oxygen carriersElectrochemical impedance spectroscopyPhosphate buffered salineSEMLayer-by-layer assemblyScanning electron microscopyHemoglobinDifferential pulse voltammetryCyclic voltammetryManganese carbonate
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Zhongqin Pan, Tingting Wu, Yang Liu, Chunmei Yu, Ning Bao, Haiying Gu,