| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 49876 | Catalysis Communications | 2015 | 4 Pages |
•New continuous-flow monolithic microreactor for MPV reduction was proposed.•Activity of different zirconium species incorporated onto silica was compared.•Catalyst stability was confirmed during long-time experiments in microreactor.
Continuous-flow monolithic silica microreactor activated with anchored isolated zirconium species was shown to be a very convenient and efficient system for chemoselective Meerwein–Ponndorf–Verley reduction. It was shown that isolated Zr4 + ions covalently bonded to the silica surface and terminated with isopropoxy/hydroxo ligands can be much more catalytically active than supported zirconia. Conversion of cyclohexanone approached 100% and excellent catalytic selectivity and stability were obtained in 8 cm long microreactor during 8 catalytic cycles. The microreactors also enable better control of undesired hydrolysis of highly reactive metal precursors during functionalisation of the monoliths.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
