Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4990108 | Separation and Purification Technology | 2017 | 31 Pages |
Abstract
A detailed study of 3-hydroxypropionic acid (3-HP) reactive extraction with tri-n-octylamine (TOA) is proposed for the first time. It aims at uncovering some solvent-solutes interactions and providing global mechanisms to better understand and design the reactive liquid-liquid extraction of 3-HP in a biotechnological process. Eleven solvents of similar molecular sizes and several chemical types (alcohols, esters and alkanes) were investigated to understand their role on the extraction ability. Alcohols were found to be the best solvents thanks to their H-bond donor characteristic and water loading that allowed good solvation of the acid-amine complexes. Further investigations were then undertaken, for n-decanol and oleyl alcohol as solvents, varying acid (0.0028-0.56Â mol/L corresponding to 0.25-50Â g/L) and amine (0-2.3Â mol/L corresponding to 0-100% v/v) concentrations. At 0.011Â mol/L (1Â g/L) of 3-HP, maximum extraction yields of 77% for n-decanol and 51% for oleyl alcohol were found for 0.46Â mol/L TOA (20% v/v). The initial TOA purity proved to have a major impact on the extraction yield at low initial acid concentration (<0.1Â mol/LÂ =Â 10Â g/L). Impurities from the TOA manufacturing process were identified as n-octylamine and di-n-octylamine and quantified in the aqueous phase after extraction. Their major effect on the extraction yield has been assessed (up to 86% decrease).
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Filtration and Separation
Authors
F. Chemarin, M. Moussa, M. Chadni, B. Pollet, P. Lieben, F. Allais, I.C. Trelea, V. Athès,